Product: ZFPL1 Antibody
Catalog: DF15570
Description: Rabbit polyclonal antibody to ZFPL1
Application: IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 33-40kD; 34kD(Calculated).
Uniprot: O95159

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ZFPL1 Antibody detects endogenous levels of ZFPL1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

D11S750; MCG4; MGC 4; ZFPL 1; Zinc finger protein like 1; Zinc finger protein MCG4; zinc-finger protein in MEN1 region;

Immunogens

Immunogen:

A synthesized peptide derived from human ZFPL1.

Uniprot:
Gene(ID):
Expression:
O95159 ZFPL1_HUMAN:

Expressed strongly in the exocrine pancreas.

Sequence:
MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFYSQAPRPPASPGRPEQHTVIHMGNPEPLTHAPRKVYDTRDDDRTPGLHGDCDDDKYRRRPALGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS

Research Backgrounds

Function:

Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.

PTMs:

Phosphorylated.

Subcellular Location:

Golgi apparatus>cis-Golgi network membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed strongly in the exocrine pancreas.

Subunit Structure:

Interacts with GOLGA2/GM130.

Family&Domains:

The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.

Belongs to the ZFPL1 family.

Restrictive clause

 

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