CCNDBP1 Antibody - #DF15478
| Product: | CCNDBP1 Antibody |
| Catalog: | DF15478 |
| Description: | Rabbit polyclonal antibody to CCNDBP1 |
| Application: | ELISA(peptide) |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 40kD(Calculated). |
| Uniprot: | O95273 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
AU022347; CCDB1_HUMAN; CCNDBP 1; Ccndbp1; Cyclin D type binding protein 1; Cyclin-D1-binding protein 1; D type cyclin interacting protein 1; DIP 1; DIP1; GCIP; Grap 2 and cyclin D interacting protein; Grap 2 cyclin D interacting protein GCIP; Grap 2 cyclin interacting protein; Grap2 and cyclin D interacting protein; Grap2 and cyclin-D-interacting protein; Grap2 cyclin D interacting protein GCIP; Grap2 cyclin interacting protein; HHM; HHM protein; Human homolog of Maid; MAID; MAID protein; Maternal inhibition of differentiation; MGC109078; OTTMUSP00000017037; RP23 263D22.2; SECC 8; SSEC 8; Stage specific embryonic cDNA 8;
Immunogens
A synthesized peptide derived from human CCNDBP1.
Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
- O95273 CCDB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
Research Backgrounds
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Phosphorylated.
Cytoplasm. Nucleus.
Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.
Belongs to the CCNDBP1 family.
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