RPL23A Antibody - #DF15375

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Product: RPL23A Antibody
Catalog: DF15375
Description: Rabbit polyclonal antibody to RPL23A
Application: IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 18kD(Calculated).
Uniprot: P62750

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RPL23A Antibody detects endogenous levels of RPL23A.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

60S ribosomal protein L23A; FLJ27455; L23A; MDA20; Melanoma differentiation-associated gene 20; Ribosomal protein L23a; RL23A_HUMAN; RPL23A;

Immunogens

Immunogen:

A synthesized peptide derived from human RPL23A.

Uniprot:

P62750(RL23A_HUMAN) >>Visit HPA database.

Gene(ID):
RPL23A(6147)
Sequence:
MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

Research Backgrounds

Function:

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.

PTMs:

N-terminus is methylated by METTL11A/NTM1.

Citrullinated by PADI4.

Subunit Structure:

Interacts with LYAR and GNL2. Interacts with MDM2; this interaction may promote MDM2-mediated p53/TP53 polyubiquitination.

Family&Domains:

Belongs to the universal ribosomal protein uL23 family.

Research Fields

· Genetic Information Processing > Translation > Ribosome.

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