LMAN2 Antibody - #DF15271

(3)  
Product: LMAN2 Antibody
Catalog: DF15271
Description: Rabbit polyclonal antibody to LMAN2
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 40kD(Calculated).
Uniprot: Q12907

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
LMAN2 Antibody detects endogenous levels of LMAN2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C5orf8; Glycoprotein GP36b; GP36B; Lectin mannose-binding 2; Lectin, mannose binding 2; LMAN 2; LMAN2; LMAN2_HUMAN; Vesicular integral membrane protein VIP36; Vesicular integral-membrane protein 36; Vesicular integral-membrane protein VIP36; VIP36;

Immunogens

Immunogen:

A synthesized peptide derived from human LMAN2.

Uniprot:

Q12907(LMAN2_HUMAN) >>Visit HPA database.

Gene(ID):
LMAN2(10960)
Expression:
Q12907 LMAN2_HUMAN:

Ubiquitous.

Sequence:
MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY

Research Backgrounds

Function:

Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity).

Subcellular Location:

Endoplasmic reticulum-Golgi intermediate compartment membrane>Single-pass type I membrane protein. Golgi apparatus membrane>Single-pass membrane protein. Endoplasmic reticulum membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum.   (View pathway)

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