Product: SSR2 Antibody
Catalog: DF15074
Description: Rabbit polyclonal antibody to SSR2
Application: IHC
Reactivity: Human, Mouse
Mol.Wt.: 20kD(Calculated).
Uniprot: P43308

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
SSR2 Antibody detects endogenous levels of SSR2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Beta SSR; DKFZp686F19123; HSD25; Signal sequence receptor subunit beta; Signal sequence receptor, beta; Signal sequence receptor, beta (translocon associated protein beta); SRIF 1; SS2R; SSR 2; SSR beta; SSR-beta; ssr2; SSRB; SSRB_HUMAN; TLAP; Translocon associated protein beta; Translocon-associated protein subunit beta; TRAP BETA; TRAP-beta; TRAPB;

Immunogens

Immunogen:

A synthesized peptide derived from human SSR2.

Uniprot:
Gene(ID):
Sequence:
MRLLSFVVLALFAVTQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKTKKN

Research Backgrounds

Function:

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Subcellular Location:

Endoplasmic reticulum membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with STING1.

Family&Domains:

Belongs to the TRAP-beta family.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum.   (View pathway)

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