ELOVL3 Antibody - #DF15022

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Product: ELOVL3 Antibody
Catalog: DF15022
Description: Rabbit polyclonal antibody to ELOVL3
Application: IHC
Reactivity: Human
Mol.Wt.: 32kD(Calculated).
Uniprot: Q9HB03

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
ELOVL3 Antibody detects endogenous levels of ELOVL3.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

3-keto acyl-CoA synthase Elovl3; CIG30; Cold-inducible glycoprotein of 30 kDa; Elongation of very long chain fatty acids protein 3; ELOV3_HUMAN; Elovl3; MGC21435;

Immunogens

Immunogen:

A synthesized peptide derived from human ELOVL3.

Uniprot:

Q9HB03(ELOV3_HUMAN) >>Visit HPA database.

Gene(ID):
ELOVL3(83401)
Expression:
Q9HB03 ELOV3_HUMAN:

Testis.

Sequence:
MVTAMNVSHEVNQLFQPYNFELSKDMRPFFEEYWATSFPIALIYLVLIAVGQNYMKERKGFNLQGPLILWSFCLAIFSILGAVRMWGIMGTVLLTGGLKQTVCFINFIDNSTVKFWSWVFLLSKVIELGDTAFIILRKRPLIFIHWYHHSTVLVYTSFGYKNKVPAGGWFVTMNFGVHAIMYTYYTLKAANVKPPKMLPMLITSLQILQMFVGAIVSILTYIWRQDQGCHTTMEHLFWSFILYMTYFILFAHFFCQTYIRPKVKAKTKSQ

Research Backgrounds

Function:

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

PTMs:

N-Glycosylated.

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Testis.

Family&Domains:

The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

Belongs to the ELO family. ELOVL3 subfamily.

Research Fields

· Metabolism > Lipid metabolism > Fatty acid elongation.

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