VPS28 Antibody - #DF14882

Product: VPS28 Antibody
Catalog: DF14882
Description: Rabbit polyclonal antibody to VPS28
Application: ELISA(peptide)
Reactivity: Human, Mouse, Rat
Mol.Wt.: 25kD(Calculated).
Uniprot: Q9UK41

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
VPS28 Antibody detects endogenous levels of VPS28.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ESCRT-I complex subunit VPS28; H-Vps28; Vacuolar protein sorting 28; Vacuolar protein sorting 28 (yeast); Vacuolar protein sorting 28 homolog (S. cerevisiae); Vacuolar protein sorting 28 homolog; Vacuolar protein sorting-associated protein 28 homolog; VPS 28; Vps28; VPS28_HUMAN; Yeast class E protein Vps28p homolog;

Immunogens

Immunogen:

A synthesized peptide derived from human VPS28.

Uniprot:

Q9UK41(VPS28_HUMAN) >>Visit HPA database.

Gene(ID):
VPS28(51160)
Sequence:
MFHGIPATPGIGAPGNKPELYEEVKLYKNAREREKYDNMAELFAVVKTMQALEKAYIKDCVSPSEYTAACSRLLVQYKAAFRQVQGSEISSIDEFCRKFRLDCPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHA

Research Backgrounds

Function:

Component of the ESCRT-I complex, a regulator of vesicular trafficking process.

Subcellular Location:

Cell membrane. Late endosome membrane>Peripheral membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and MVB12A or MVB12B in a 1:1:1:1 stoichiometry. Interacts with TSG101, VPS37B, VPS37C, MVB12A and MVB12B. Component of an ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, VPS37A and UBAP1 in a 1:1:1:1 stoichiometry. Interacts WITH VPS36; the interaction mediates the association with the ESCRT-II complex. Interacts with SNF8 and VPS25. Interacts with CEP55.

Family&Domains:

Belongs to the VPS28 family.

Research Fields

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

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