ZNF410 Antibody - #DF14815

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Product: ZNF410 Antibody
Catalog: DF14815
Description: Rabbit polyclonal antibody to ZNF410
Application: WB
Reactivity: Human, Mouse
Mol.Wt.: 52kD(Calculated).
Uniprot: Q86VK4

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MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ZNF410 Antibody detects endogenous levels of ZNF410.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Another partner for ARF 1; APA 1; APA1; Clones 23667 and 23775 zinc finger protein; D12Ertd748e; Zfp410; Zinc finger protein 410; Zinc finger protein APA 1; Zinc finger protein APA-1; ZN410_HUMAN; Znf410;

Immunogens

Immunogen:

A synthesized peptide derived from human ZNF410.

Uniprot:

Q86VK4(ZN410_HUMAN) >>Visit HPA database.

Gene(ID):
ZNF410(57862)
Expression:
Q86VK4 ZN410_HUMAN:

Widely expressed.

Sequence:
MLSDELESKPELLVQFVQNTSIPLGQGLVESEAKDITCLSLLPVTEASECSRLMLPDDTTNHSNSSKEVPSSAVLRSLRVNVGPDGEETRAQTVQKSPEFLSTSESSSLLQDLQPSDSTSFILLNLTRAGLGSSAEHLVFVQDEAEDSGNDFLSSESTDSSIPWFLRVQELAHDSLIAATRAQLAKNAKTSSNGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNLPNTNSILGVDDEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVLTAVNPQELLNQGDLTERRT

Research Backgrounds

Function:

Transcription factor that activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence.

PTMs:

Sumoylated. Sumoylation increases its half-life, possibly by blocking ubiquitin-mediated degradation.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed.

Subunit Structure:

Interacts with CDKN2A/p14ARF.

Restrictive clause

 

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