DERA Antibody - #DF14813

(3)  
Product: DERA Antibody
Catalog: DF14813
Description: Rabbit polyclonal antibody to DERA
Application: WB IHC
Reactivity: Human, Mouse
Mol.Wt.: 35kD(Calculated).
Uniprot: Q9Y315

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
DERA Antibody detects endogenous levels of DERA.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Deoxyriboaldolase; 2 deoxyribose 5 phosphate aldolase homolog C. elegans; CGI 26; CGI26; DEOC; DEOC_HUMAN; Deoxyriboaldolase; Deoxyribose phosphate aldolase like; DERA; Phosphodeoxyriboaldolase; Putative deoxyribose phosphate aldolase; Putative deoxyribose-phosphate aldolase;

Immunogens

Immunogen:

A synthesized peptide derived from human DERA.

Uniprot:

Q9Y315(DEOC_HUMAN) >>Visit HPA database.

Gene(ID):
DERA(51071)
Expression:
Q9Y315 DEOC_HUMAN:

Mainly expressed in liver, lung and colon.

Sequence:
MSAHNRGTELDLSWISKIQVNHPAVLRRAEQIQARRTVKKEWQAAWLLKAVTFIDLTTLSGDDTSSNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNIPVASVAAGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRKACGEAHLKTILATGELGTLTNVYKASMIAMMAGSDFIKTSTGKETVNATFPVAIVMLRAIRDFFWKTGNKIGFKPAGGIRSAKDSLAWLSLVKEELGDEWLKPELFRIGASTLLSDIERQIYHHVTGRYAAYHDLPMS

Research Backgrounds

Function:

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.

Subcellular Location:

Cytoplasm. Cytoplasmic granule. Nucleus.
Note: Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Mainly expressed in liver, lung and colon.

Subunit Structure:

Interacts with YBX1.

Family&Domains:

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

Research Fields

· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.

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