BDH2 Antibody - #DF14214

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Product: BDH2 Antibody
Catalog: DF14214
Description: Rabbit polyclonal antibody to BDH2
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 27kD; 27kD(Calculated).
Uniprot: Q9BUT1

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
BDH2 Antibody detects endogenous levels of total BDH2.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

3 hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase type 2; BDH 2; BDH2; BDH2_HUMAN; Dehydrogenase/reductase (SDR family) member 6; Dehydrogenase/reductase SDR family member 6; DHRS6; EFA6R; FLJ13261; Oxidoreductase ucpA; PRO20933; R beta hydroxybutyrate dehydrogenase; R-beta-hydroxybutyrate dehydrogenase; SDR15C1; Short chain dehydrogenase/reductase family 15C member 1; UCPA OR; UNQ6308;

Immunogens

Immunogen:

A synthesized peptide derived from Human BDH2.

Uniprot:

Q9BUT1(BDH2_HUMAN) >>Visit HPA database.

Gene(ID):
BDH2(56898)
Expression:
Q9BUT1 BDH2_HUMAN:

Detected in liver (at protein level).

Sequence:
MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL

Research Backgrounds

Function:

Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity). Also acts as a 3-hydroxybutyrate dehydrogenase.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in liver (at protein level).

Subunit Structure:

Homotetramer.

Family&Domains:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Research Fields

· Metabolism > Lipid metabolism > Synthesis and degradation of ketone bodies.

· Metabolism > Carbohydrate metabolism > Butanoate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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