SDF4 Antibody - #DF14122

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Product: SDF4 Antibody
Catalog: DF14122
Description: Rabbit polyclonal antibody to SDF4
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 30~40kD; 42kD(Calculated).
Uniprot: Q9BRK5

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
SDF4 Antibody detects endogenous levels of total SDF4.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

45 kDa calcium-binding protein; Cab45; CAB45_HUMAN; Calcium binding protein; PSEC0034; SDF 4; SDF-4; SDF4; Stromal cell derived factor 4; Stromal cell-derived factor 4;

Immunogens

Immunogen:

A synthesized peptide derived from Human SDF4.

Uniprot:

Q9BRK5(CAB45_HUMAN) >>Visit HPA database.

Gene(ID):
SDF4(51150)
Expression:
Q9BRK5 CAB45_HUMAN:

Ubiquitous. Isoform 5 is expressed in pancreas.

Sequence:
MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHEEF

Research Backgrounds

Function:

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.

Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

Subcellular Location:

Golgi apparatus lumen.

Cytoplasm. Cell membrane. Cell projection>Bleb.
Note: Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous. Isoform 5 is expressed in pancreas.

Subunit Structure:

Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.

Family&Domains:

Binds calcium via its EF-hands (By similarity). Isoform 5 binds calcium.

Belongs to the CREC family.

Restrictive clause

 

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