ACOT7 Antibody | Affinity Biosciences

Product:	ACOT7 Antibody
Catalog:	DF14107
Description:	Rabbit polyclonal antibody to ACOT7
Application:	ELISA(peptide)
Reactivity:	Human, Mouse, Rat
Mol.Wt.:	40kD; 42kD(Calculated).
Uniprot:	O00154

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Blocking Peptides

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Clonality:

Polyclonal

Specificity:

ACOT7 Antibody detects endogenous levels of total ACOT7.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

ACH1; ACOT 7; ACOT7; ACT; Acyl CoA thioesterase 7; Acyl CoA thioesterase long chain; Acyl-CoA thioesterase 7; BACH; BACH_HUMAN; Brain acyl CoA hydrolase; Brain acyl-CoA hydrolase; CTE-II; CTE-IIa; Cytosolic acyl coenzyme A thioester hydrolase; hBACH; LACH; LACH1; Long chain acyl-CoA thioester hydrolase;

Immunogens

Immunogen:

A synthesized peptide derived from Human ACOT7.

Uniprot:

O00154(BACH_HUMAN) >>Visit HPA database.

Gene(ID):

ACOT7(11332)

Expression:

O00154 BACH_HUMAN:

Isoform 4 is expressed exclusively in brain.

Sequence:

O00154 BACH_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MKLLARALRLCEFGRQASSRRLVAGQGCVGPRRGCCAPVQVVGPRADLPPCGACITGRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVNVMSENILTGAKKLTNKATLWYVPLSLKNVDKVLEVPPVVYSRQEQEEEGRKRYEAQKLERMETKWRNGDIVQPVLNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDSSQKRYRAASAFFTYVSLSQEGRSLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHAEPQP

Research Backgrounds

O00154_BACH_HUMAN

Function:

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A thioesterase 7/ACOT7 preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain.

Subcellular Location:

Cytoplasm>Cytosol.

Cytoplasm>Cytosol.

Mitochondrion.

Mitochondrion.

Tissue Specificity:

Isoform 4 is expressed exclusively in brain.

Subunit Structure:

Homohexamer.

Family&Domains:

Both HotDog ACOT-type hydrolase domains are required for efficient activity.

Research Fields

· Metabolism > Lipid metabolism > Fatty acid elongation.

· Metabolism > Lipid metabolism > Biosynthesis of unsaturated fatty acids.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

ACOT7 Antibody - #DF14107