SLC26A3 Antibody | Affinity Biosciences

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DF14099 at 1/100 staining mouse liver tissue by IHC-P.

Product:	SLC26A3 Antibody
Catalog:	DF14099
Description:	Rabbit polyclonal antibody to SLC26A3
Application:	IHC
Reactivity:	Human, Mouse, Rat
Mol.Wt.:	85kD(Calculated).
Uniprot:	P40879

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Clonality:

Polyclonal

Specificity:

SLC26A3 Antibody detects endogenous levels of total SLC26A3.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

Chloride anion exchanger; CLD; Congenital chloride diarrhea; Down regulated in adenoma; Down regulated in adenoma protein; Down-regulated in adenoma; DRA; Protein DRA; S26A3_HUMAN; SLC26A3; Solute carrier family 26 member 3;

Immunogens

Immunogen:

A synthesized peptide derived from Human SLC26A3.

Uniprot:

P40879(S26A3_HUMAN) >>Visit HPA database.

Gene(ID):

SLC26A3(1811)

Sequence:

P40879 S26A3_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF

Research Backgrounds

P40879_S26A3_HUMAN

Function:

Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

PTMs:

N-glycosylation is required for efficient cell surface expression, and protection from proteolytic degradation.

Subcellular Location:

Apical cell membrane>Multi-pass membrane protein. Membrane>Multi-pass membrane protein.
Note: Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity).

Subunit Structure:

Interacts with CFTR, SLC26A6 and SLC9A3R1 (By similarity). Interacts with PDZK1.

Family&Domains:

Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.

Research Fields

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Mineral absorption.

Restrictive clause

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For Research Use Only.
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SLC26A3 Antibody - #DF14099