SRD5A1 Antibody - #DF13930

Product: SRD5A1 Antibody
Catalog: DF13930
Description: Rabbit polyclonal antibody to SRD5A1
Application: ELISA(peptide)
Reactivity: Human, Mouse, Rat
Mol.Wt.: 29kD; 29kD(Calculated).
Uniprot: P18405

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
SRD5A1 Antibody detects endogenous levels of total SRD5A1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

3 oxo 5 alpha steroid 4 dehydrogenase 1; 3 oxo 5 alpha steroid delta 4 dehydrogenase alpha 1; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1,5-alpha reductase; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; 5 alpha reductase; S5A1_HUMAN; S5AR 1; S5AR; SR type 1; SRD5A 1; Srd5a1; Steroid 5 alpha reductase 1; Steroid 5 alpha reductase alpha polypeptide 1 (3 oxo 5 alpha steroid delta 4 dehydrogenase alpha 1); Steroid 5 alpha reductase alpha polypeptide 1; Steroid 5 alpha reductase type I; Steroid 5-alpha-reductase 1;

Immunogens

Immunogen:

A synthesized peptide derived from Human SRD5A1.

Uniprot:

P18405(S5A1_HUMAN) >>Visit HPA database.

Gene(ID):
SRD5A1(6715)
Expression:
P18405 S5A1_HUMAN:

Liver and prostate (at a low level).

Sequence:
MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF

Research Backgrounds

Function:

Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

Subcellular Location:

Microsome membrane>Multi-pass membrane protein. Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Liver and prostate (at a low level).

Family&Domains:

Belongs to the steroid 5-alpha reductase family.

Research Fields

· Metabolism > Lipid metabolism > Steroid hormone biosynthesis.

Restrictive clause

 

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For Research Use Only.
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