PPAPDC3 Antibody - #DF13870
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
C9orf67; Phosphatidic acid phosphatase type 2 domain-containing protein 3; PPAC3_HUMAN; Ppapdc3; Probable lipid phosphate phosphatase PPAPDC3;
Immunogens
A synthesized peptide derived from Human PPAPDC3.
- Q8NBV4 PLPP7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPASQSRARARDRNNVLNRAEFLSLNQPPKGGPEPRSSGRKASGPSAQPPPAGDGARERRQSQQLPEEDCMQLNPSFKGIAFNSLLAIDICMSKRLGVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVKSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPSLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWALCVGLSRVMIGRHHVTDVLSGFVIGYLQFRLVELVWMPSSTCQMLISAW
Research Backgrounds
Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity).
Nucleus envelope. Endoplasmic reticulum membrane. Membrane>Multi-pass membrane protein.
Note: Both the N- and C-terminal are exposed to the cytoplasm/nucleoplasm.
Homo and heterooligomer. Interacts with MTOR; controls MTOR-dependent IGF2 expression during myoblast differentiation (By similarity).
Belongs to the PA-phosphatase related phosphoesterase family.
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