DDX39 Antibody - #DF13848
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
ATP dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; BAT1; BAT1L; DDX39; DDXL; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 isoform 2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; DEAD box protein 39; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; Eukaryotic initiation factor 4a; Nuclear RNA helicase URH49; Nuclear RNA helicase, DECD variant of DEAD box family; UAP56 related helicase; UAP56 related helicase, 49 kDa; URH49; wu:fc87b12; zgc:55881;
Immunogens
A synthesized peptide derived from Human DDX39.
Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland.
- O00148 DX39A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEQDVENDLLDYDEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
Research Backgrounds
Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus.
Nucleus. Cytoplasm.
Note: Can translocate to the cytoplasm in the presence of MX1.
Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland.
Binds ALYREF/THOC4 and DDX39B/BAT1. Interacts with SARNP. Interacts with human cytomegalovirus/HHV-5 protein UL69. Interacts with MX1. Interacts with MCM3AP isoform GANP.
Belongs to the DEAD box helicase family. DECD subfamily.
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