Product: IL17D Antibody
Catalog: DF13823
Description: Rabbit polyclonal antibody to IL17D
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 22kD; 22kD(Calculated).
Uniprot: Q8TAD2

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
IL17D Antibody detects endogenous levels of total IL17D.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

IL 17D; IL 22; IL 27; IL-17D; IL-27; IL17D; IL17D_HUMAN; IL27; Interleukin 17D; Interleukin 27; Interleukin-17D; Interleukin-27;

Immunogens

Immunogen:

A synthesized peptide derived from Human IL17D.

Uniprot:
Gene(ID):
Expression:
Q8TAD2 IL17D_HUMAN:

Expressed preferentially in adipose, skeletal muscle and CNS.

Sequence:
MLVAGFLLALPPSWAAGAPRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP

Research Backgrounds

Function:

Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed preferentially in adipose, skeletal muscle and CNS.

Family&Domains:

Belongs to the IL-17 family.

Research Fields

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway.   (View pathway)

· Organismal Systems > Immune system > IL-17 signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Th17 cell differentiation.   (View pathway)

Restrictive clause

 

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