Phospho-SALL1 (Ser941) Antibody - #AF3528

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Product: Phospho-SALL1 (Ser941) Antibody
Catalog: AF3528
Description: Rabbit polyclonal antibody to Phospho-SALL1 (Ser941)
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 140kD(Calculated).
Uniprot: Q9NSC2
RRID: AB_2846842

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 100ul $350 In stock
 200ul $450 In stock

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
Phospho-SALL1 (Ser941) Antibody detects endogenous levels of SALL1 only when phosphorylated at Ser941.
RRID:
AB_2846842
Cite Format: Affinity Biosciences Cat# AF3528, RRID:AB_2846842.
Conjugate:
Unconjugated.
Purification:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HSal1; Sal like protein 1; Sal-1; Sal-like protein 1; Sal1; SALL1; SALL1_HUMAN; Spalt-like transcription factor 1; TBS; Zinc finger protein 794; Zinc finger protein SALL1; Zinc finger protein Spalt-1;

Immunogens

Immunogen:

A synthesized peptide derived from human SALL1 around the phosphorylation site of Ser941.

Uniprot:

Q9NSC2(SALL1_HUMAN) >>Visit HPA database.

Gene(ID):
SALL1(6299)
Expression:
Q9NSC2 SALL1_HUMAN:

Highest levels in kidney. Lower levels in adult brain (enriched in corpus callosum, lower expression in substantia nigra) and liver.

Sequence:
MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLLHKKNCTKNQLVLIVNENPASPPETFSPSPPPDNPDEQMNDTVNKTDQVDCSDLSEHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGGKLAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASNPLLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPTSTGIPYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENMEDCPEGSIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANGLSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFPEMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPPIPGSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEIVTS

PTMs - Q9NSC2 As Substrate

Site PTM Type Enzyme
T28 Phosphorylation
S34 Phosphorylation
S152 Phosphorylation
S153 Phosphorylation
S154 Phosphorylation
S155 Phosphorylation
S324 Phosphorylation
S337 Phosphorylation
T349 Phosphorylation
S460 Phosphorylation
T472 Phosphorylation
K478 Methylation
K493 Acetylation
S586 Phosphorylation
S590 Phosphorylation
S593 Phosphorylation
S595 Phosphorylation
S620 Phosphorylation
T729 Phosphorylation
Y753 Phosphorylation
S847 Phosphorylation
S854 Phosphorylation
S941 Phosphorylation
S943 Phosphorylation
S985 Phosphorylation
K1086 Sumoylation
S1119 Phosphorylation
T1155 Phosphorylation
T1157 Phosphorylation
S1198 Phosphorylation
T1307 Phosphorylation

Research Backgrounds

Function:

Transcriptional repressor involved in organogenesis.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highest levels in kidney. Lower levels in adult brain (enriched in corpus callosum, lower expression in substantia nigra) and liver.

Subunit Structure:

Interacts with HDAC1, HDAC2, RBBP4, RBPP7, MTA1 and MTA2 (By similarity). Interacts with CCNQ. Probably associates with NuRD histone deacetylase complex (HDAC).

Family&Domains:

Belongs to the sal C2H2-type zinc-finger protein family.

Restrictive clause

 

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