Product: ESD Antibody
Catalog: DF13683
Description: Rabbit polyclonal antibody to ESD
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Horse, Rabbit, Dog
Mol.Wt.: 31kDa, 40 kDa; 31kD(Calculated).
Uniprot: P10768
RRID: AB_2846702

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Horse(100%), Rabbit(88%), Dog(88%)
Clonality:
Polyclonal
Specificity:
ESD Antibody detects endogenous levels of total ESD.
RRID:
AB_2846702
Cite Format: Affinity Biosciences Cat# DF13683, RRID:AB_2846702.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EC 3.1.2.12; Es-10; Es10; ESD; ESTD_HUMAN; Esterase 10; Esterase D; Esterase D formylglutathione hydrolase; FGH; FGH, included; FLJ11763; Methylumbelliferyl acetate deacetylase; MGC139609; OTTHUMP00000018374; OTTHUMP00000040929; S formylglutathione hydrolase; S-formylglutathione hydrolase; S-formylglutathione hydrolase, included; Sid 478; sid478;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
88
Rabbit
88
Bovine
75
Sheep
75
Xenopus
75
Zebrafish
75
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P10768 As Substrate

Site PTM Type Enzyme
K4 Acetylation
K4 Ubiquitination
K10 Acetylation
K10 Ubiquitination
C11 S-Nitrosylation
K17 Ubiquitination
C28 S-Nitrosylation
K29 Ubiquitination
K31 Ubiquitination
K39 Acetylation
K39 Ubiquitination
S144 Phosphorylation
S149 Phosphorylation
K167 Ubiquitination
S170 Phosphorylation
C176 S-Nitrosylation
C181 S-Nitrosylation
K185 Acetylation
K185 Ubiquitination
K186 Acetylation
K186 Ubiquitination
S197 Phosphorylation
K198 Ubiquitination
K200 Acetylation
K200 Ubiquitination
Y202 Phosphorylation
K209 Ubiquitination
S214 Phosphorylation
K246 Ubiquitination
K247 Ubiquitination
Y258 Phosphorylation
Y262 Phosphorylation
Y263 Phosphorylation
K278 Acetylation

Research Backgrounds

Function:

Serine hydrolase involved in the detoxification of formaldehyde.

Subcellular Location:

Cytoplasm. Cytoplasmic vesicle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the esterase D family.

Research Fields

· Metabolism > Global and overview maps > Carbon metabolism.

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.