TROY Antibody - #DF13610
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13610, RRID:AB_2846629.
Fold/Unfold
AL023044; AW123854; TAJ alpha; TAJ; TAJ-alpha; TNFRSF19; TNFRSF19 tumor necrosis factor receptor superfamily, member 19; TNR19_HUMAN; Toxicity and JNK inducer; TRADE; TROY; Tumor necrosis factor receptor superfamily member 19; UNQ1888/PRO4333;
Immunogens
Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
- Q9NS68 TNR19_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSICGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAVPVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQVRQRLGSL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NS68 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S110 | Phosphorylation | Uniprot | |
| Y122 | Phosphorylation | Uniprot | |
| T125 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| S241 | Phosphorylation | Uniprot | |
| T244 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot |
Research Backgrounds
Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Membrane>Single-pass type I membrane protein.
Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
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