KC1AL Antibody - #DF13605
Product: | KC1AL Antibody |
Catalog: | DF13605 |
Description: | Rabbit polyclonal antibody to KC1AL |
Application: | WB IF/ICC |
Reactivity: | Human, Mouse, Rat |
Mol.Wt.: | 40kDa, 33 kDa; 39kD(Calculated). |
Uniprot: | Q8N752 |
RRID: | AB_2846624 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13605, RRID:AB_2846624.
Fold/Unfold
Casein kinase 1, alpha 1 like; casein kinase 1, alpha 1-like; Casein kinase I alpha S like; Casein kinase I isoform alpha like; CK1; CKI alpha like; MGC33182; OTTHUMP00000018267; RP11 532O21.2;
Immunogens
- Q8N752 KC1AL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
PTMs - Q8N752 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K53 | Acetylation | Uniprot | |
Y59 | Phosphorylation | Uniprot | |
K62 | Acetylation | Uniprot | |
K83 | Acetylation | Uniprot | |
K130 | Ubiquitination | Uniprot | |
T146 | Phosphorylation | Uniprot | |
K152 | Ubiquitination | Uniprot | |
K162 | Ubiquitination | Uniprot | |
T184 | Phosphorylation | Uniprot | |
S206 | Phosphorylation | Uniprot | |
Y209 | Phosphorylation | Uniprot | |
Y213 | Phosphorylation | Uniprot | |
K240 | Ubiquitination | Uniprot | |
T287 | Phosphorylation | Uniprot | |
Y292 | Phosphorylation | Uniprot | |
Y294 | Phosphorylation | Uniprot | |
K302 | Ubiquitination | Uniprot |
PTMs - Q8N752 As Enzyme
Research Backgrounds
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).
Cytoplasm.
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Research Fields
· Environmental Information Processing > Signal transduction > Wnt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Hedgehog signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
· Human Diseases > Cancers: Specific types > Breast cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Human Diseases > Cancers: Specific types > Gastric cancer. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.