ALDH9A1 Antibody - #DF13562
| Product: | ALDH9A1 Antibody |
| Catalog: | DF13562 |
| Description: | Rabbit polyclonal antibody to ALDH9A1 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 53kDa; 54kD(Calculated). |
| Uniprot: | P49189 |
| RRID: | AB_2846581 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13562, RRID:AB_2846581.
Fold/Unfold
4 trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; aldh9A1; E3; Gamma aminobutyraldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH;
Immunogens
Detected in brain (at protein level) (PubMed:8645224). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain (PubMed:8786138). Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
- P49189 AL9A1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTGTFVVSQPLNYRGGARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49189 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| R15 | Methylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| S233 | Phosphorylation | Uniprot | |
| K239 | Ubiquitination | Uniprot | |
| K246 | Ubiquitination | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| K298 | Acetylation | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| K303 | Acetylation | Uniprot | |
| K303 | Ubiquitination | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K316 | Ubiquitination | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| K366 | Ubiquitination | Uniprot | |
| K461 | Acetylation | Uniprot | |
| K462 | Acetylation | Uniprot | |
| Y476 | Phosphorylation | Uniprot |
Research Backgrounds
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
Cytoplasm>Cytosol.
Detected in brain (at protein level). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
Homotetramer.
Belongs to the aldehyde dehydrogenase family.
Research Fields
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Carbohydrate metabolism > Ascorbate and aldarate metabolism.
· Metabolism > Lipid metabolism > Fatty acid degradation.
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Amino acid metabolism > Histidine metabolism.
· Metabolism > Amino acid metabolism > Tryptophan metabolism.
· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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