B7-H6 Antibody - #DF13516
| Product: | B7-H6 Antibody |
| Catalog: | DF13516 |
| Description: | Rabbit polyclonal antibody to B7-H6 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Mol.Wt.: | 50kDa; 51kD(Calculated). |
| Uniprot: | Q68D85 |
| RRID: | AB_2846535 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13516, RRID:AB_2846535.
Fold/Unfold
B7 homolog 6; B7-H6; B7H6; B7H6_HUMAN; DKFZp686O24166; Natural cytotoxicity triggering receptor 3 ligand 1; NCR3LG1; Putative Ig like domain containing protein DKFZp686O24166/DKFZp686I21167;
Immunogens
Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B-lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level).
- Q68D85 NR3L1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTWRAAASTCAALLILLWALTTEGDLKVEMMAGGTQITPLNDNVTIFCNIFYSQPLNITSMGITWFWKSLTFDKEVKVFEFFGDHQEAFRPGAIVSPWRLKSGDASLRLPGIQLEEAGEYRCEVVVTPLKAQGTVQLEVVASPASRLLLDQVGMKENEDKYMCESSGFYPEAINITWEKQTQKFPHPIEISEDVITGPTIKNMDGTFNVTSCLKLNSSQEDPGTVYQCVVRHASLHTPLRSNFTLTAARHSLSETEKTDNFSIHWWPISFIGVGLVLLIVLIPWKKICNKSSSAYTPLKCILKHWNSFDTQTLKKEHLIFFCTRAWPSYQLQDGEAWPPEGSVNINTIQQLDVFCRQEGKWSEVPYVQAFFALRDNPDLCQCCRIDPALLTVTSGKSIDDNSTKSEKQTPREHSDAVPDAPILPVSPIWEPPPATTSTTPVLSSQPPTLLLPLQ
PTMs - Q68D85 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N43 | N-Glycosylation | Uniprot | |
| N57 | N-Glycosylation | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| R90 | Methylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| S102 | Phosphorylation | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| N208 | N-Glycosylation | Uniprot | |
| Y226 | Phosphorylation | Uniprot | |
| N242 | N-Glycosylation | Uniprot | |
| K290 | Ubiquitination | Uniprot | |
| Y295 | Phosphorylation | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| S394 | Phosphorylation | Uniprot | |
| K396 | Ubiquitination | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| K407 | Ubiquitination | Uniprot |
Research Backgrounds
Triggers NCR3-dependent natural killer cell activation.
Cell membrane>Single-pass type I membrane protein.
Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B-lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level).
Monomer. Interacts specifically with NCR3, but not with other natural killer cell-activating receptors, including NCR1, NCR2 and KLRK1.
The C-terminal part is similar to retroviral Gag protein. This putative protein seems to be the result of a fusion between an Ig-like domain-containing protein and a ERV.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.