Product: KCNK9 Antibody
Catalog: DF13498
Description: Rabbit polyclonal antibody to KCNK9
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Rabbit, Chicken, Xenopus
Mol.Wt.: 42kDa; 42kD(Calculated).
Uniprot: Q9NPC2
RRID: AB_2846517

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Chicken(83%), Xenopus(83%)
Clonality:
Polyclonal
Specificity:
KCNK9 Antibody detects endogenous levels of total KCNK9.
RRID:
AB_2846517
Cite Format: Affinity Biosciences Cat# DF13498, RRID:AB_2846517.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Acid sensitive potassium channel protein TASK 3; K2p9.1; KT3.2; MGC138268; MGC138270; Potassium channel TASK3; Potassium channel, subfamily K, member 9 (TASK 3); Potassium channel, subfamily K, member 9; TASK 3; TWIK related acid sensitive K+ channel 3;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9NPC2 KCNK9_HUMAN:

Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.

Sequence:
MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCTCYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHSFTDHQRLMKRRKSV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Rabbit
100
Xenopus
83
Chicken
83
Sheep
0
Dog
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NPC2 As Substrate

Site PTM Type Enzyme
S56 Phosphorylation
Y59 Phosphorylation
Y113 Phosphorylation
Y138 Phosphorylation
K144 Acetylation
Y286 Phosphorylation
T341 Phosphorylation
S349 Phosphorylation
S352 Phosphorylation
S353 Phosphorylation
S373 Phosphorylation P17612 (PRKACA)

Research Backgrounds

Function:

pH-dependent, voltage-insensitive, background potassium channel protein.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung.

Subunit Structure:

Homodimer (Probable). Heterodimer with KCNK1.

Family&Domains:

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Research Fields

· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.

Restrictive clause

 

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