FHL1 Antibody - #DF13482
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| Product: | FHL1 Antibody |
| Catalog: | DF13482 |
| Description: | Rabbit polyclonal antibody to FHL1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Sheep, Rabbit, Dog |
| Mol.Wt.: | 36kDa; 36kD(Calculated). |
| Uniprot: | Q13642 |
| RRID: | AB_2846501 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13482, RRID:AB_2846501.
Fold/Unfold
bA535K18.1; FHL 1; FHL 1B; FHL-1; FHL1; FHL1 protein; FHL1_HUMAN; FHL1A; FHL1B; FLH1A; Four and a half LIM domains 1; Four and a half LIM domains protein 1; Four and a half Lin11 Isl 1 and Mec 3 domains 1; four-and-a-half Lin11; Isl-1 and Mec-3; KYO T; KYOT, mouse, homolog of; LIM protein SLIMMER; MGC111107; RAM14-1; RBMX1A; RBMX1B; RBP associated molecule 14-1; RP11-535K18.1; Skeletal muscle LIM protein 1; Skeletal muscle LIM-protein 1; SLIM 1; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA;
Immunogens
A synthesized peptide derived from human FHL1, corresponding to a region within C-terminal amino acids.
Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle.
- Q13642 FHL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVKAPVWWPMKDNPGTTTASTAKNAP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13642 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K22 | Acetylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| R59 | Methylation | Uniprot | |
| T79 | Phosphorylation | Uniprot | |
| K86 | Sumoylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| T138 | Phosphorylation | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| Y213 | Phosphorylation | Uniprot |
Research Backgrounds
May have an involvement in muscle development or hypertrophy.
Cytoplasm.
Cytoplasm. Nucleus.
Nucleus. Cytoplasm>Cytosol.
Note: Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes.
Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle.
Research Fields
· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway. (View pathway)
References
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