Statherin Antibody - #DF13407

(3)  
Product: Statherin Antibody
Catalog: DF13407
Description: Rabbit polyclonal antibody to Statherin
Application: WB IHC
Reactivity: Human
Mol.Wt.: 7kDa; 7kD(Calculated).
Uniprot: P02808
RRID: AB_2846426

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
Statherin Antibody detects endogenous levels of total Statherin.
RRID:
AB_2846426
Cite Format: Affinity Biosciences Cat# DF13407, RRID:AB_2846426.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

STAT_HUMAN; STATH; Statherin; Statherin precursor; STR;

Immunogens

Immunogen:
Uniprot:

P02808(STAT_HUMAN) >>Visit HPA database.

Gene(ID):
STATH(6779)
Expression:
P02808 STAT_HUMAN:

Secreted by parotid and submandibular glands.

Sequence:
MKFLVFAFILALMVSMIGADSSEEKFLRRIGRFGYGYGPYQPVPEQPLYPQPYQPQYQQYTF

PTMs - P02808 As Substrate

Site PTM Type Enzyme
S15 Phosphorylation
S21 Phosphorylation
S22 Phosphorylation
Y49 Phosphorylation

Research Backgrounds

Function:

Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.

PTMs:

Substrate for transglutaminase-2. More than 95% of the cyclized peptide is cyclo-statherin Q-37, and less than 5% is cyclo-statherin Q-39. Cyclized forms account for about 1% of total statherin in saliva.

Sulfated on tyrosine residues.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Secreted by parotid and submandibular glands.

Family&Domains:

Belongs to the histatin/statherin family.

Research Fields

· Organismal Systems > Digestive system > Salivary secretion.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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