Product: HBZ Antibody
Catalog: DF13400
Description: Rabbit polyclonal antibody to HBZ
Application: WB IHC
Reactivity: Human
Prediction: Pig, Bovine
Mol.Wt.: 15kDa; 16kD(Calculated).
Uniprot: P02008
RRID: AB_2846419

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%)
Clonality:
Polyclonal
Specificity:
HBZ Antibody detects endogenous levels of total HBZ.
RRID:
AB_2846419
Cite Format: Affinity Biosciences Cat# DF13400, RRID:AB_2846419.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HBAZ; HBAZ_HUMAN; HBZ 2; HBZ; HBZ2; Hemoglobin subunit zeta; Hemoglobin zeta; Hemoglobin zeta chain; Zeta globin; Zeta-globin;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P02008 HBAZ_HUMAN:

Detected in fetal erythrocytes (at protein level).

Sequence:
MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Horse
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P02008 As Substrate

Site PTM Type Enzyme
S2 Acetylation
S2 Phosphorylation
K5 Acetylation
T24 Phosphorylation
T29 Phosphorylation
S36 Phosphorylation
T40 Phosphorylation
K41 Acetylation
K41 Ubiquitination
Y43 Phosphorylation
S53 Phosphorylation
K62 Ubiquitination
S73 Phosphorylation
S82 Phosphorylation
K83 Acetylation
K83 Ubiquitination
Y90 Phosphorylation
K100 Acetylation

Research Backgrounds

Function:

The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.

Tissue Specificity:

Detected in fetal erythrocytes (at protein level).

Subunit Structure:

Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in fetal hemoglobin Portland-1. Heterotetramer of two zeta chains and two beta chains in hemoglobin Portland-2, detected in fetuses and neonates with homozygous alpha-thalassemia.

Family&Domains:

Belongs to the globin family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.