hair cortex Cytokeratin Antibody - #DF13328
| Product: | hair cortex Cytokeratin Antibody |
| Catalog: | DF13328 |
| Description: | Rabbit polyclonal antibody to hair cortex Cytokeratin |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 48kDa; 48kD(Calculated). |
| Uniprot: | Q6A162 |
| RRID: | AB_2846347 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13328, RRID:AB_2846347.
Fold/Unfold
CK-40; Cytokeratin-40; hair cortex Cytokeratin; K1C40_HUMAN; K40; Keratin; Keratin, type I cytoskeletal 40; Keratin-40; Krt40; type I cytoskeletal 40; Type I hair keratin Ka36;
Immunogens
Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level).
- Q6A162 K1C40_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSAYVICTVENCCL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6A162 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y103 | Phosphorylation | Uniprot | |
| T311 | Phosphorylation | Uniprot | |
| S313 | Phosphorylation | Uniprot |
Research Backgrounds
May play a role in late hair differentiation.
Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level).
Heterotetramer of two type I and two type II keratins.
Belongs to the intermediate filament family.
Research Fields
· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)
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