Product: MTA2 Antibody
Catalog: DF13292
Description: Rabbit polyclonal antibody to MTA2
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 75kDa; 75kD(Calculated).
Uniprot: O94776
RRID: AB_2846311

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Xenopus(88%)
Clonality:
Polyclonal
Specificity:
MTA2 Antibody detects endogenous levels of total MTA2.
RRID:
AB_2846311
Cite Format: Affinity Biosciences Cat# DF13292, RRID:AB_2846311.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

DKFZp686F2281; Mata1l1; Metastasis associated 1 family member 2; Metastasis associated 1 like 1; Metastasis associated gene 1 like 1; Metastasis associated gene family member 2; Metastasis associated protein 2; Metastasis associated protein MTA 2; Metastasis associated protein MTA2; Mmta2; MTA1 L1 protein; MTA1L1; p53 target protein in deacetylase complex; PID;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O94776 MTA2_HUMAN:

Widely expressed.

Sequence:
MAANMYRVGDYVYFENSSSNPYLVRRIEELNKTANGNVEAKVVCLFRRRDISSSLNSLADSNAREFEEESKQPGVSEQQRHQLKHRELFLSRQFESLPATHIRGKCSVTLLNETDILSQYLEKEDCFFYSLVFDPVQKTLLADQGEIRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARALDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQIISVGSKPGMNGAGFQKGLTCESCHTTQSAQWYAWGPPNMQCRLCASCWIYWKKYGGLKTPTQLEGATRGTTEPHSRGHLSRPEAQSLSPYTTSANRAKLLAKNRQTFLLQTTKLTRLARRMCRDLLQPRRAARRPYAPINANAIKAECSIRLPKAAKTPLKIHPLVRLPLATIVKDLVAQAPLKPKTPRGTKTPINRNQLSQNRGLGGIMVKRAYETMAGAGVPFSANGRPLASGIRSSSQPAAKRQKLNPADAPNPVVFVATKDTRALRKALTHLEMRRAARRPNLPLKVKPTLIAVRPPVPLPAPSHPASTNEPIVLED

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
88
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O94776 As Substrate

Site PTM Type Enzyme
Y11 Phosphorylation
Y13 Phosphorylation
Y22 Phosphorylation
K32 Ubiquitination
K41 Ubiquitination
S52 Phosphorylation
S54 Phosphorylation
S57 Phosphorylation
S61 Phosphorylation
K71 Ubiquitination
K152 Acetylation
K152 Ubiquitination
R160 Methylation
R169 Methylation
K173 Methylation
K173 Ubiquitination
K177 Ubiquitination
R188 Methylation
S221 Phosphorylation
K282 Ubiquitination
K285 Ubiquitination
K320 Ubiquitination
K332 Acetylation
Y335 Phosphorylation
Y339 Phosphorylation
K341 Acetylation
K341 Ubiquitination
S352 Phosphorylation
S393 Phosphorylation
Y397 Phosphorylation
K405 Ubiquitination
T406 Phosphorylation
S427 Phosphorylation
S433 Phosphorylation
S435 Phosphorylation P24941 (CDK2)
Y437 Phosphorylation
T438 Phosphorylation P24941 (CDK2)
T439 Phosphorylation P24941 (CDK2)
S440 Phosphorylation P24941 (CDK2)
T453 Phosphorylation
T458 Phosphorylation
T459 Phosphorylation
K460 Ubiquitination
Y483 Phosphorylation
S496 Phosphorylation
T505 Phosphorylation
K508 Ubiquitination
T519 Phosphorylation
K522 Ubiquitination
K531 Acetylation
T534 Phosphorylation
K539 Ubiquitination
T540 Phosphorylation
S548 Phosphorylation
R551 Methylation
K559 Acetylation
K559 Methylation
K559 Ubiquitination
Y562 Phosphorylation
S587 Phosphorylation
K592 Acetylation
K611 Ubiquitination
T621 Phosphorylation

Research Backgrounds

Function:

May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed.

Subunit Structure:

Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD) (By similarity). Interacts with HDAC7 and MBD3 (By similarity). Interacts with p53/TP53. Interacts with MINT. Interacts with PIMREG. Interacts with NACC2. Interacts with ERCC6.

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For Research Use Only.
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