Brachyury / Bry Antibody - #DF13238
Product: | Brachyury / Bry Antibody |
Catalog: | DF13238 |
Description: | Rabbit polyclonal antibody to Brachyury / Bry |
Application: | WB IHC IF/ICC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Sheep, Chicken |
Mol.Wt.: | 47kDa; 47kD(Calculated). |
Uniprot: | O15178 |
RRID: | AB_2846257 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13238, RRID:AB_2846257.
Fold/Unfold
BRAC_HUMAN; Brachyury homolog; Brachyury protein; Bry; MGC104817; Protein T; SAVA; T; T brachyury homolog; T brachyury transcription factor; T Protein; T, brachyury homolog (mouse); TFT; Transcription factor T;
Immunogens
Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level).
- O15178 TBXT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGGALSLPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSNGLGAQFFRGSPAHYTPLTHPVSAPSSSGSPLYEGAAAATDIVDSQYDAAAQGRLIASWTPVSPPSM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15178 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S12 | Phosphorylation | Uniprot | |
Y15 | Phosphorylation | Uniprot | |
T65 | Phosphorylation | Uniprot | |
T149 | Phosphorylation | Uniprot | |
S162 | Phosphorylation | Uniprot | |
S431 | Phosphorylation | Uniprot |
Research Backgrounds
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
Nucleus.
Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level).
Monomer.
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