Elastase Antibody - #DF13226

(3)  
Product: Elastase Antibody
Catalog: DF13226
Description: Rabbit polyclonal antibody to Elastase
Application: WB IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 29kDa; 29kD(Calculated).
Uniprot: P08861
RRID: AB_2846245

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
Elastase Antibody detects endogenous levels of total Elastase.
RRID:
AB_2846245
Cite Format: Affinity Biosciences Cat# DF13226, RRID:AB_2846245.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CELA3B; Chymotrypsin like elastase family member 3B; ELA3B; Elastase 3B; Elastase IIIB; Protease E;

Immunogens

Immunogen:
Uniprot:

P08861(CEL3B_HUMAN) >>Visit HPA database.

Gene(ID):
CELA3B(23436)
Expression:
P08861 CEL3B_HUMAN:

Pancreas. Not detectable in keratinocytes.

Sequence:
MMLRLLSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETIASH

PTMs - P08861 As Substrate

Site PTM Type Enzyme
S7 Phosphorylation
S8 Phosphorylation
S23 Phosphorylation

Research Backgrounds

Function:

Efficient protease with alanine specificity but only little elastolytic activity.

Tissue Specificity:

Pancreas. Not detectable in keratinocytes.

Family&Domains:

Belongs to the peptidase S1 family. Elastase subfamily.

Research Fields

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Protein digestion and absorption.

Restrictive clause

 

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