Product: NME5 Antibody
Catalog: DF13188
Description: Rabbit polyclonal antibody to NME5
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 24 kDa; 24kD(Calculated).
Uniprot: P56597
RRID: AB_2846148

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(88%), Bovine(100%), Horse(89%), Sheep(100%), Rabbit(100%)
Clonality:
Polyclonal
Specificity:
NME5 Antibody detects endogenous levels of total NME5.
RRID:
AB_2846148
Cite Format: Affinity Biosciences Cat# DF13188, RRID:AB_2846148.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Inhibitor of p53 induced apoptosis beta; Inhibitor of p53-induced apoptosis-beta; IPIA beta; IPIA-beta; NDK-H 5; NDK5_HUMAN; NDP kinase homolog 5; NM23 H5; nm23-H5; Nm23-M5; NM23H5; NME/NM23 family member 5; NME5; Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nonmetastatic cells 5, protein expressed in; Nonmetastatic protein 23, homolog 5; Nucleoside diphosphate kinase homolog 5; Radial spoke 23 homolog; RSPH23; Testis specific nm23 homolog; Testis-specific nm23 homolog;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P56597 NDK5_HUMAN:

Specifically expressed in testis germinal cells.

Sequence:
MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Rabbit
100
Horse
89
Zebrafish
88
Xenopus
67
Chicken
67
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P56597 As Substrate

Site PTM Type Enzyme
Y58 Phosphorylation

Research Backgrounds

Function:

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).

Tissue Specificity:

Specifically expressed in testis germinal cells.

Family&Domains:

Belongs to the NDK family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.