MYOM1 Antibody - #DF13169
(3)
| Product: | MYOM1 Antibody |
| Catalog: | DF13169 |
| Description: | Rabbit polyclonal antibody to MYOM1 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 190 kDa; 188kD(Calculated). |
| Uniprot: | P52179 |
| RRID: | AB_2846129 |
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Prediction:
Pig(91%), Horse(100%), Sheep(91%), Rabbit(100%), Dog(100%), Xenopus(91%)
Clonality:
Polyclonal
Specificity:
MYOM1 Antibody detects endogenous levels of total MYOM1.
RRID:
AB_2846129
Cite Format: Affinity Biosciences Cat# DF13169, RRID:AB_2846129.
Cite Format: Affinity Biosciences Cat# DF13169, RRID:AB_2846129.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
190 kDa connectin-associated protein; 190 kDa titin-associated protein; EH myomesin; MGC134946; MGC134947; MYOM1; MYOM1_HUMAN; Myomesin (M protein) 1 (190kD); Myomesin 1 (skelemin) 185kDa; Myomesin 1 185kDa; Myomesin 1, 185kDa; Myomesin family member 1; Myomesin-1; Skelemin;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- P52179 MYOM1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEAFRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAKHSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Horse
100
Dog
100
Rabbit
100
Pig
91
Sheep
91
Xenopus
91
Bovine
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P52179 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| Y13 | Phosphorylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| Y29 | Phosphorylation | Uniprot | |
| Y39 | Phosphorylation | Uniprot | |
| Y46 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| S67 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| Y136 | Phosphorylation | Uniprot | |
| S149 | Phosphorylation | Uniprot | |
| T152 | Phosphorylation | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| T257 | Phosphorylation | Uniprot | |
| T309 | Phosphorylation | Uniprot | |
| Y311 | Phosphorylation | Uniprot | |
| Y372 | Phosphorylation | Uniprot | |
| Y397 | Phosphorylation | Uniprot | |
| Y399 | Phosphorylation | Uniprot | |
| S401 | Phosphorylation | Uniprot | |
| Y444 | Phosphorylation | Uniprot | |
| T458 | Phosphorylation | Uniprot | |
| T572 | Phosphorylation | Uniprot | |
| S618 | Phosphorylation | Uniprot | |
| Y708 | Phosphorylation | Uniprot | |
| T753 | Phosphorylation | Uniprot | |
| T966 | Phosphorylation | Uniprot | |
| S1054 | Phosphorylation | Uniprot | |
| K1083 | Acetylation | Uniprot | |
| S1170 | Phosphorylation | Uniprot | |
| S1177 | Phosphorylation | Uniprot | |
| S1270 | Phosphorylation | Uniprot | |
| Y1277 | Phosphorylation | Uniprot | |
| Y1392 | Phosphorylation | Uniprot | |
| Y1426 | Phosphorylation | Uniprot | |
| S1462 | Phosphorylation | Uniprot | |
| S1497 | Phosphorylation | Uniprot | |
| Y1551 | Phosphorylation | Uniprot | |
| Y1555 | Phosphorylation | Uniprot | |
| S1677 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
Subcellular Location:
Cytoplasm>Myofibril>Sarcomere>M line.
Subunit Structure:
Homodimer (By similarity). Interacts with TTN/titin (By similarity). Interacts with PNKD.
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