LARS Antibody - #DF13121

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Product: LARS Antibody
Catalog: DF13121
Description: Rabbit polyclonal antibody to LARS
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 140 kDa; 134kD(Calculated).
Uniprot: Q9P2J5
RRID: AB_2846081

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
LARS Antibody detects endogenous levels of total LARS.
RRID:
AB_2846081
Cite Format: Affinity Biosciences Cat# DF13121, RRID:AB_2846081.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

cytoplasmic; Cytoplasmic leucyl tRNA synthetase; Cytosolic leucyl tRNA synthetase; FLJ10595; FLJ21788; hr025Cl; HSPC 192; HSPC192; KIAA1352; LARS 1; Lars; LARS1; Leucine translase; Leucine tRNA ligase; Leucine--tRNA ligase; Leucyl tRNA synthetase cytoplasmic; Leucyl-tRNA synthetase; LeuRS; LEUS; LRS; PIG 44; PIG44; Proliferation inducing gene 44; RNTLS; SYLC_HUMAN;

Immunogens

Immunogen:
Uniprot:

Q9P2J5(SYLC_HUMAN) >>Visit HPA database.

Gene(ID):
LARS(51520)
Sequence:
MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVLMENIVYLTNSLELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGDTIIYLVH

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9P2J5 As Substrate

Site PTM Type Enzyme
K5 Ubiquitination
K9 Ubiquitination
K15 Ubiquitination
K18 Ubiquitination
K23 Ubiquitination
S35 Phosphorylation
K39 Ubiquitination
K43 Ubiquitination
K45 Acetylation
K45 Ubiquitination
S66 Phosphorylation
K69 Ubiquitination
K82 Ubiquitination
K98 Ubiquitination
K155 Ubiquitination
K162 Ubiquitination
S167 Phosphorylation
K173 Ubiquitination
K193 Acetylation
K193 Ubiquitination
K198 Ubiquitination
Y214 Phosphorylation
T224 Phosphorylation
K235 Acetylation
K243 Acetylation
K243 Ubiquitination
Y264 Phosphorylation
K268 Ubiquitination
K270 Ubiquitination
Y275 Phosphorylation
S277 Phosphorylation
K278 Ubiquitination
K283 Ubiquitination
K329 Ubiquitination
S335 Phosphorylation
K341 Ubiquitination
K350 Ubiquitination
T367 Phosphorylation
K381 Acetylation
K384 Ubiquitination
S394 Phosphorylation
S396 Phosphorylation
K407 Ubiquitination
K459 Ubiquitination
K466 Ubiquitination
Y468 Phosphorylation
Y473 Phosphorylation
K497 Ubiquitination
Y507 Phosphorylation
K512 Ubiquitination
K540 Acetylation
K541 Ubiquitination
K548 Ubiquitination
Y637 Phosphorylation
K641 Ubiquitination
K647 Ubiquitination
T648 Phosphorylation
K659 Ubiquitination
Y666 Phosphorylation
T702 Phosphorylation
S714 Phosphorylation
K716 Ubiquitination
S718 Phosphorylation
K719 Ubiquitination
S720 Phosphorylation
T721 Phosphorylation
T728 Phosphorylation
K733 Ubiquitination
S735 Phosphorylation
R795 Methylation
K807 Ubiquitination
K814 Ubiquitination
K822 Ubiquitination
K832 Ubiquitination
K914 Ubiquitination
K921 Acetylation
K923 Acetylation
K924 Acetylation
K927 Ubiquitination
K932 Ubiquitination
Y944 Phosphorylation
K965 Ubiquitination
K970 Ubiquitination
K983 Ubiquitination
Y985 Phosphorylation
K988 Ubiquitination
K1002 Ubiquitination
S1042 Phosphorylation
K1047 Ubiquitination
K1056 Ubiquitination
K1133 Ubiquitination
Y1135 Phosphorylation
K1138 Ubiquitination
K1154 Ubiquitination
Y1173 Phosphorylation

Research Backgrounds

Function:

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the class-I aminoacyl-tRNA synthetase family.

Research Fields

· Genetic Information Processing > Translation > Aminoacyl-tRNA biosynthesis.

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