HIBCH Antibody - #DF13060
| Product: | HIBCH Antibody |
| Catalog: | DF13060 |
| Description: | Rabbit polyclonal antibody to HIBCH |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 38 kDa; 43kD(Calculated). |
| Uniprot: | Q6NVY1 |
| RRID: | AB_2846021 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13060, RRID:AB_2846021.
Fold/Unfold
3 hydroxyisobutyryl Coenzyme A hydrolase; 3 hydroxyisobutyryl Coenzyme A hydrolase, mitochondrial; 3-hydroxyisobutyryl-CoA hydrolase; 3-hydroxyisobutyryl-coenzyme A hydrolase; BETA HYDROXYISOBUTYRYL COENZYME A HYDROLASE; HIB CoA hydrolase; HIB-CoA hydrolase; HIBCH; HIBCH_HUMAN; HIBCoA hydrolase; HIBYL CoA H; HIBYL CoAH; HIBYL-CoA-H; HIBYLCoA H; HIBYLCoAH; mitochondrial;
Immunogens
Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung.
- Q6NVY1 HIBCH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6NVY1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K42 | Ubiquitination | Uniprot | |
| K73 | Acetylation | Uniprot | |
| K92 | Acetylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| K233 | Ubiquitination | Uniprot | |
| S234 | Phosphorylation | Uniprot | |
| K237 | Ubiquitination | Uniprot | |
| Y247 | Phosphorylation | Uniprot | |
| K252 | Ubiquitination | Uniprot | |
| S258 | Phosphorylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| Y330 | Phosphorylation | Uniprot | |
| K353 | Acetylation | Uniprot | |
| S356 | Phosphorylation | Uniprot |
Research Backgrounds
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
Mitochondrion.
Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung.
Belongs to the enoyl-CoA hydratase/isomerase family.
Research Fields
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.
· Metabolism > Carbohydrate metabolism > Propanoate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
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