Product: GNPDA1 Antibody
Catalog: DF13046
Description: Rabbit polyclonal antibody to GNPDA1
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 33 kDa; 33kD(Calculated).
Uniprot: P46926
RRID: AB_2846007

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(92%), Horse(100%), Sheep(92%), Rabbit(92%)
Clonality:
Polyclonal
Specificity:
GNPDA1 Antibody detects endogenous levels of total GNPDA1.
RRID:
AB_2846007
Cite Format: Affinity Biosciences Cat# DF13046, RRID:AB_2846007.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EC 3.5.99.6; GlcN6P deaminase 1; Glucosamine 6 phosphate deaminase 1; Glucosamine 6 phosphate isomerase 1; Glucosamine-6-phosphate deaminase 1; Glucosamine-6-phosphate isomerase 1; GNPDA 1; GNPDA1; GNPI; GNPI1_HUMAN; HLN; KIAA0060; Oscillin; Putative glucosamine 6 phosphate isomerase;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
92
Sheep
92
Rabbit
92
Dog
75
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P46926 As Substrate

Site PTM Type Enzyme
K50 Acetylation
K50 Ubiquitination
K51 Acetylation
K51 Ubiquitination
K57 Ubiquitination
K64 Acetylation
K64 Ubiquitination
K67 Ubiquitination
T68 Phosphorylation
K124 Ubiquitination
T157 Phosphorylation
K160 Ubiquitination
T161 Phosphorylation
T166 Phosphorylation
K253 Ubiquitination
K256 Ubiquitination
K264 Ubiquitination
Y270 Phosphorylation
S271 Phosphorylation
K273 Ubiquitination
T277 Phosphorylation
S282 Phosphorylation
Y287 Phosphorylation

Research Backgrounds

Function:

Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity).

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homohexamer.

Family&Domains:

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

Research Fields

· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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For Research Use Only.
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