GGCT Antibody - #DF13037

(2)  
Product: GGCT Antibody
Catalog: DF13037
Description: Rabbit polyclonal antibody to GGCT
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 21 kDa; 21kD(Calculated).
Uniprot: O75223
RRID: AB_2845998

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(90%), Horse(100%), Sheep(90%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
GGCT Antibody detects endogenous levels of total GGCT.
RRID:
AB_2845998
Cite Format: Affinity Biosciences Cat# DF13037, RRID:AB_2845998.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C7orf24; CRF21; Cytochrome c-releasing factor 21; Gamma glutamyl cyclotransferase; Gamma-glutamylcyclotransferase; GCTG; GGC; Ggct; GGCT_HUMAN;

Immunogens

Immunogen:
Uniprot:

O75223(GGCT_HUMAN) >>Visit HPA database.

Gene(ID):
GGCT(79017)
Sequence:
MANSGCKDVTGPDEESFLYFAYGSNLLTERIHLRNPSAAFFCVARLQDFKLDFGNSQGKTSQTWHGGIATIFQSPGDEVWGVVWKMNKSNLNSLDEQEGVKSGMYVVIEVKVATQEGKEITCRSYLMTNYESAPPSPQYKKIICMGAKENGLPLEYQEKLKAIEPNDYTGKVSEEIEDIIKKGETQTL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Rabbit
100
Bovine
90
Sheep
90
Chicken
70
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75223 As Substrate

Site PTM Type Enzyme
S16 Phosphorylation
S24 Phosphorylation
S37 Phosphorylation
S93 Phosphorylation
K118 Ubiquitination
S136 Phosphorylation
K140 Ubiquitination
K141 Ubiquitination
K159 Ubiquitination
K161 Ubiquitination
Y168 Phosphorylation
S173 Phosphorylation
T187 Phosphorylation

Research Backgrounds

Function:

Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the gamma-glutamylcyclotransferase family.

Research Fields

· Metabolism > Metabolism of other amino acids > Glutathione metabolism.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.