GCSH Antibody - #DF13036
| Product: | GCSH Antibody |
| Catalog: | DF13036 |
| Description: | Rabbit polyclonal antibody to GCSH |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 15 kDa; 19kD(Calculated). |
| Uniprot: | P23434 |
| RRID: | AB_2845997 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13036, RRID:AB_2845997.
Immunogens
- P23434 GCSH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALRVVRSVRALLCTLRAVPSPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWVTTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P23434 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T43 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| S160 | Phosphorylation | Uniprot | |
| Y164 | Phosphorylation | Uniprot | |
| K166 | Acetylation | Uniprot |
Research Backgrounds
The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
Mitochondrion.
Interacts with GLDC (By similarity). The glycine cleavage system is composed of four proteins: P (GLDC), T (GCST), L (DLD) and H (GCSH).
Belongs to the GcvH family.
Research Fields
· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.
· Metabolism > Carbohydrate metabolism > Glyoxylate and dicarboxylate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
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For Research Use Only.
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