Product: FMO5 Antibody
Catalog: DF13018
Description: Rabbit polyclonal antibody to FMO5
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 60 kDa; 60kD(Calculated).
Uniprot: P49326
RRID: AB_2845979

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Zebrafish(83%), Bovine(92%), Horse(83%), Sheep(92%), Rabbit(92%), Dog(92%), Xenopus(92%)
Clonality:
Polyclonal
Specificity:
FMO5 Antibody detects endogenous levels of total FMO5.
RRID:
AB_2845979
Cite Format: Affinity Biosciences Cat# DF13018, RRID:AB_2845979.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Dimethylaniline monooxygenase [N oxide forming] 5; Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; FMO 5; FMO5; FMO5_HUMAN; Hepatic flavin containing monooxygenase 5; Hepatic flavin-containing monooxygenase 5;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P49326 FMO5_HUMAN:

Expressed in fetal and adult liver.

Sequence:
MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
92
Sheep
92
Dog
92
Xenopus
92
Rabbit
92
Horse
83
Zebrafish
83
Chicken
75
Pig
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P49326 As Substrate

Site PTM Type Enzyme
S54 Phosphorylation
Y56 Phosphorylation
S58 Phosphorylation
Y104 Phosphorylation
Y171 Phosphorylation
Y177 Phosphorylation
S280 Phosphorylation
T284 Phosphorylation
T398 Phosphorylation
S410 Phosphorylation
T501 Phosphorylation
S509 Phosphorylation
S512 Phosphorylation

Research Backgrounds

Function:

In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.

Subcellular Location:

Microsome membrane. Endoplasmic reticulum membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in fetal and adult liver.

Family&Domains:

Belongs to the FMO family.

Research Fields

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

Restrictive clause

 

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For Research Use Only.
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