FARS2 Antibody - #DF13001
| Product: | FARS2 Antibody |
| Catalog: | DF13001 |
| Description: | Rabbit polyclonal antibody to FARS2 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog |
| Mol.Wt.: | 48 kDa; 52kD(Calculated). |
| Uniprot: | O95363 |
| RRID: | AB_2845962 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13001, RRID:AB_2845962.
Fold/Unfold
dJ236A3.1 (phenylalanine tRNA synthetase); dJ520B18.2 (FARS1 (phenylalanine tRNA synthetase)); FARS1; Fars2; HSPC320; Phenylalanine translase; Phenylalanine tRNA ligase 2, mitochondrial; Phenylalanine tRNA ligase; Phenylalanine tRNA synthetase 1 (mitochondrial); Phenylalanine tRNA synthetase 2 (mitochondrial); Phenylalanine--tRNA ligase; Phenylalanyl tRNA synthetase 2; Phenylalanyl-tRNA synthetase, mitochondrial; PheRS; SYFM_HUMAN;
Immunogens
- O95363 SYFM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKYPAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIHQALQEAAVQLLGVEGRF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95363 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K56 | Ubiquitination | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| K202 | Acetylation | Uniprot | |
| T246 | Phosphorylation | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| T387 | Phosphorylation | Uniprot |
Research Backgrounds
Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins.
Mitochondrion matrix. Mitochondrion.
Monomer.
Belongs to the class-II aminoacyl-tRNA synthetase family.
Research Fields
· Genetic Information Processing > Translation > Aminoacyl-tRNA biosynthesis.
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