ENPP4 Antibody - #DF12978
| Product: | ENPP4 Antibody |
| Catalog: | DF12978 |
| Description: | Rabbit polyclonal antibody to ENPP4 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 60 kDa; 52kD(Calculated). |
| Uniprot: | Q9Y6X5 |
| RRID: | AB_2845939 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12978, RRID:AB_2845939.
Fold/Unfold
;KIAA0879; 4933413N07Rik; AA986363; AI195364; E-NPP 4; Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative); Ectonucleotide pyrophosphatase/phosphodiesterase family member 4; ENPP4; ENPP4_HUMAN; Gm90; mKIAA0879; NPP-4; NPP4;
Immunogens
- Q9Y6X5 ENPP4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLLVILLFSGLITGFRSDSSSSLPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKHFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDVPIHDTISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYYTLIDLSPVAAILPKINRTEVYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQKLGDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNGTFGHTKCLLVDQWCINLPEAIAIVIGSLLVLTMLTCLIIIMQNRLSVPRPFSRLQLQEDDDDPLIG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y6X5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| S23 | Phosphorylation | Uniprot | |
| T68 | Phosphorylation | Uniprot | |
| T70 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| N155 | N-Glycosylation | Uniprot | |
| N166 | N-Glycosylation | Uniprot | |
| N386 | N-Glycosylation | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| S439 | Phosphorylation | Uniprot |
Research Backgrounds
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
Cell membrane>Single-pass type I membrane protein.
Expressed on the surface of vascular endothelia.
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
Research Fields
· Metabolism > Nucleotide metabolism > Purine metabolism.
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