C17orf28 Antibody - #DF12865

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Product: C17orf28 Antibody
Catalog: DF12865
Description: Rabbit polyclonal antibody to C17orf28
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken
Mol.Wt.: 89 kDa; 89kD(Calculated).
Uniprot: Q8IV36
RRID: AB_2845826

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
C17orf28 Antibody detects endogenous levels of total C17orf28.
RRID:
AB_2845826
Cite Format: Affinity Biosciences Cat# DF12865, RRID:AB_2845826.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C17orf28; Chromosome 17 open reading frame 28; CQ028_HUMAN; DMC1; Down regulated in multiple cancers 1; Down-regulated in multiple cancers 1; Downregulated in multiple cancer 1; FLJ43526; HID 1; HID1; HID1 domain containing; HID1 domain containing protein; Hypothetical protein LOC283987; Protein hid 1 homolog; Protein HID1; UPF0663 transmembrane protein C17orf28;

Immunogens

Immunogen:
Uniprot:

Q8IV36(HID1_HUMAN) >>Visit HPA database.

Gene(ID):
HID1(283987)
Expression:
Q8IV36 HID1_HUMAN:

Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines.

Sequence:
MGSTDSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHSEKEKQIVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEDDEHARPLAESLLLAIADLLFCPDFTVQSHRRSTVDSAEDVHSLDSCEYIWEAGVGFAHSPQPNYIHDMNRMELLKLLLTCFSEAMYLPPAPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSASSASPTVDGTTTGTAMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILFFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSIRVPMDIPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSAAQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRSIFHQLANLPTDPPTIHKALQRRRRTPEPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPEPQQSLEDGSPAKGEPSQAWREQRRPSTSSASGQWSPTPEWVLSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPVWYDTDVKLFEIQRV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Xenopus
75
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8IV36 As Substrate

Site PTM Type Enzyme
G2 Myristoylation
T4 Phosphorylation
S6 Phosphorylation
T121 Phosphorylation
S144 Phosphorylation
S170 Phosphorylation
K363 Ubiquitination
S430 Phosphorylation
S559 Phosphorylation
T584 Phosphorylation
S589 Phosphorylation
T591 Phosphorylation
S593 Phosphorylation
T597 Phosphorylation
S616 Phosphorylation
T620 Phosphorylation
S640 Phosphorylation
S648 Phosphorylation
S653 Phosphorylation
S670 Phosphorylation
T671 Phosphorylation
S672 Phosphorylation
S673 Phosphorylation
S675 Phosphorylation
S679 Phosphorylation
T681 Phosphorylation
Y747 Phosphorylation

Research Backgrounds

Function:

May play an important role in the development of cancers in a broad range of tissues.

Subcellular Location:

Cytoplasm. Golgi apparatus membrane>Lipid-anchor.
Note: Shuttles between the cytosol and the Golgi apparatus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines.

Family&Domains:

Belongs to the hid-1 family.

Restrictive clause

 

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