ACAT2 Antibody - #DF12807
| Product: | ACAT2 Antibody |
| Catalog: | DF12807 |
| Description: | Rabbit polyclonal antibody to ACAT2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 41 kDa; 60kD(Calculated). |
| Uniprot: | O75908 |
| RRID: | AB_2845768 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12807, RRID:AB_2845768.
Fold/Unfold
ACACT2; ACAT 2; ACAT2; Acyl Co A: cholesterol acyltransferase 2; Acyl CoA:cholesterol acyltransferase 2; acyl coenzyme A cholestrol acyltransferase 2; Acyl coenzyme A:cholesterol acyltransferase 2; ARGP2; Cholesterol acyltransferase 2; Sterol O acyl transferase 2; SOAT2;SOAT 2;Sterol O-acyltransferase 2;Cholesterol acyltransferase 2;
Immunogens
- O75908 SOAT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75908 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T285 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Expression seems confined in hepatocytes and enterocytes.
May form homo- or heterodimers.
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Research Fields
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Organismal Systems > Digestive system > Cholesterol metabolism.
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