TXNDC5 Antibody - #DF12787
Product: | TXNDC5 Antibody |
Catalog: | DF12787 |
Description: | Rabbit polyclonal antibody to TXNDC5 |
Application: | WB IF/ICC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig |
Mol.Wt.: | 48 kDa; 48kD(Calculated). |
Uniprot: | Q8NBS9 |
RRID: | AB_2845748 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12787, RRID:AB_2845748.
Fold/Unfold
EndoPDI; Endoplasmic reticulum protein ERp46; Endoplasmic reticulum resident protein 46; Endothelial protein disulphide isomerase; ER protein 46; ERp46; Hcc 2; MGC3178; PDIA15; Protein disulfide isomerase family A member 15; STRF8; Thioredoxin domain containing 5 (endoplasmic reticulum); Thioredoxin domain containing 5; Thioredoxin domain containing protein 5; Thioredoxin domain-containing protein 5; Thioredoxin like protein p46; Thioredoxin related protein; Thioredoxin-like protein p46; TLP46; TXND5_HUMAN; TXNDC 5; Txndc5;
Immunogens
- Q8NBS9 TXND5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPARPGRLLPLLARPAALTALLLLLLGHGGGGRWGARAQEAAAAAADGPPAADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAKDEL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NBS9 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T72 | O-Glycosylation | Uniprot | |
S108 | Phosphorylation | Uniprot | |
K113 | Ubiquitination | Uniprot | |
Y115 | Phosphorylation | Uniprot | |
K118 | Ubiquitination | Uniprot | |
T122 | Phosphorylation | Uniprot | |
S125 | Phosphorylation | Uniprot | |
S129 | Phosphorylation | Uniprot | |
R134 | Methylation | Uniprot | |
K143 | Ubiquitination | Uniprot | |
K150 | Ubiquitination | Uniprot | |
K221 | Methylation | Uniprot | |
K241 | Ubiquitination | Uniprot | |
K244 | Ubiquitination | Uniprot | |
T248 | Phosphorylation | Uniprot | |
Y251 | Phosphorylation | Uniprot | |
Y289 | Phosphorylation | Uniprot | |
K344 | Ubiquitination | Uniprot | |
K366 | Ubiquitination | Uniprot | |
K390 | Acetylation | Uniprot | |
S419 | Phosphorylation | Uniprot | |
S426 | Phosphorylation | Uniprot | |
K429 | Ubiquitination | Uniprot |
Research Backgrounds
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity).
Endoplasmic reticulum lumen.
Belongs to the protein disulfide isomerase family.
Research Fields
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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