Product: Syntaxin3 Antibody
Catalog: DF12760
Description: Rabbit polyclonal antibody to Syntaxin3
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Rabbit, Dog, Chicken
Mol.Wt.: 33 kDa; 33kD(Calculated).
Uniprot: Q13277
RRID: AB_2845721

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(86%), Dog(100%), Chicken(82%)
Clonality:
Polyclonal
Specificity:
Syntaxin3 Antibody detects endogenous levels of total Syntaxin3.
RRID:
AB_2845721
Cite Format: Affinity Biosciences Cat# DF12760, RRID:AB_2845721.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ30906; Stx3; STX3_HUMAN; STX3A; Syntaxin 3A; Syntaxin-3;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
86
Chicken
82
Sheep
73
Xenopus
73
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q13277 As Substrate

Site PTM Type Enzyme
K9 Ubiquitination
T14 Phosphorylation
K100 Ubiquitination
K117 Ubiquitination
K126 Ubiquitination
K159 Ubiquitination
K188 Ubiquitination
S192 Phosphorylation
S206 Phosphorylation
S207 Phosphorylation

Research Backgrounds

Function:

Potentially involved in docking of synaptic vesicles at presynaptic active zones.

Subcellular Location:

Membrane>Single-pass type IV membrane protein.
Note: Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with REEP6 (By similarity). Interacts with PRPH2 in rod and cone photoreceptors (By similarity). Interacts with ROM1 (By similarity). Interacts with SNAP25 (By similarity). Interacts with VAMP2 (By similarity).

Family&Domains:

Belongs to the syntaxin family.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

Restrictive clause

 

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For Research Use Only.
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