SLC19A3 Antibody - #DF12741

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Product: SLC19A3 Antibody
Catalog: DF12741
Description: Rabbit polyclonal antibody to SLC19A3
Application: WB
Reactivity: Human, Mouse, Rat
Mol.Wt.: 66 kDa; 56kD(Calculated).
Uniprot: Q9BZV2
RRID: AB_2845702

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
SLC19A3 Antibody detects endogenous levels of total SLC19A3.
RRID:
AB_2845702
Cite Format: Affinity Biosciences Cat# DF12741, RRID:AB_2845702.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Solute carrier family 19 member 3; Thiamine transporter 2; thTr 2; THTR2;

Immunogens

Immunogen:
Uniprot:

Q9BZV2(S19A3_HUMAN) >>Visit HPA database.

Gene(ID):
SLC19A3(80704)
Expression:
Q9BZV2 S19A3_HUMAN:

Widely expressed but most abundant in placenta, kidney and liver.

Sequence:
MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPGCEEQKPTSEILSTSGKLNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSIQFLVYGSYFAVIAGIFLMRSMYITYSTKSQKDVQSPAPSENPDVSHPEEESNIIMSTKL

PTMs - Q9BZV2 As Substrate

Site PTM Type Enzyme
N45 N-Glycosylation
Y151 Phosphorylation
T152 Phosphorylation
S212 Phosphorylation
T234 Phosphorylation

Research Backgrounds

Function:

Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity.

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed but most abundant in placenta, kidney and liver.

Family&Domains:

Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

Research Fields

· Organismal Systems > Digestive system > Vitamin digestion and absorption.

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