RPH3AL Antibody - #DF12726
| Product: | RPH3AL Antibody |
| Catalog: | DF12726 |
| Description: | Rabbit polyclonal antibody to RPH3AL |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Rabbit, Dog |
| Mol.Wt.: | 38 kDa; 34kD(Calculated). |
| Uniprot: | Q9UNE2 |
| RRID: | AB_2845687 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12726, RRID:AB_2845687.
Fold/Unfold
Gm1753; No C2 domains protein; Noc2; Rab effector Noc2; Rabphilin 3A-like (without C2 domains); Rabphilin 3A-like; Rabphilin-3A-like protein; RPH3AL; RPH3L_HUMAN;
Immunogens
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
- Q9UNE2 RPH3L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSCLG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UNE2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S128 | Phosphorylation | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| S210 | Phosphorylation | Uniprot |
Research Backgrounds
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.
Cytoplasm. Cytoplasmic vesicle>Secretory vesicle membrane.
Note: Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
Recruited to dense-core vesicles through specific interaction with RAB27A in endocrine cells. Interacts with RAB3A, RAB3B, RAB3C and RAB3D. Interacts with ZYX (By similarity).
The N-terminus of the RabBD domain is necessary and sufficient for interaction with RAB27A.
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