PLA2G12A Antibody - #DF12699
| Product: | PLA2G12A Antibody |
| Catalog: | DF12699 |
| Description: | Rabbit polyclonal antibody to PLA2G12A |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Xenopus |
| Mol.Wt.: | 21 kDa; 21kD(Calculated). |
| Uniprot: | Q9BZM1 |
| RRID: | AB_2845660 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12699, RRID:AB_2845660.
Fold/Unfold
EC 3.1.1.4; Group XII secreted phospholipase A2; Group XIIA secreted phospholipase A2; Group XIIA secretory phospholipase A2; Group XIIA secretory phospholipase A2 precursor; GXII; GXII sPLA2; PG12A_HUMAN; phosphatidylcholine 2 acylhydrolase 12A; Phosphatidylcholine 2 acylhydrolase GXII; Phosphatidylcholine 2-acylhydrolase 12A; Phospholipase A2 group XIIA; PLA2G12; Pla2g12a; ROSSY; sPLA2 XII; sPLA2-XII;
Immunogens
- Q9BZM1 PG12A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPYLDSQRAACRCHYEEKTDL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BZM1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y130 | Phosphorylation | Uniprot |
Research Backgrounds
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Secreted. Cytoplasm.
Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
Belongs to the phospholipase A2 family.
Research Fields
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Lipid metabolism > Ether lipid metabolism.
· Metabolism > Lipid metabolism > Arachidonic acid metabolism.
· Metabolism > Lipid metabolism > Linoleic acid metabolism.
· Metabolism > Lipid metabolism > alpha-Linolenic acid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Circulatory system > Vascular smooth muscle contraction. (View pathway)
· Organismal Systems > Digestive system > Pancreatic secretion.
· Organismal Systems > Digestive system > Fat digestion and absorption.
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