GGPS1 Antibody - #DF12617
| Product: | GGPS1 Antibody |
| Catalog: | DF12617 |
| Description: | Rabbit polyclonal antibody to GGPS1 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 35 kDa; 35kD(Calculated). |
| Uniprot: | O95749 |
| RRID: | AB_2845579 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12617, RRID:AB_2845579.
Fold/Unfold
(2E; 6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase 1; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; Geranylgeranyl pyrophosphate synthetase; Geranyltranstransferase; GGPP synthase; GGPP synthetase; GGPPS; GGPPS_HUMAN; GGPPS1; GGPPSase; GGPS1; OTTHUMP00000036073; OTTHUMP00000216161; OTTHUMP00000216163; OTTHUMP00000216164;
Immunogens
- O95749 GGPPS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95749 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K3 | Ubiquitination | Uniprot | |
| Y16 | Phosphorylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K25 | Acetylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| S87 | Phosphorylation | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| S203 | Phosphorylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| Y272 | Phosphorylation | Uniprot | |
| K273 | Ubiquitination | Uniprot | |
| R278 | Methylation | Uniprot |
Research Backgrounds
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
Cytoplasm.
Abundantly expressed in testis. Found in other tissues to a lower extent.
Homohexamer; trimer of homodimers.
Belongs to the FPP/GGPP synthase family.
Research Fields
· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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