GART Antibody - #DF12613

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Product: GART Antibody
Catalog: DF12613
Description: Rabbit polyclonal antibody to GART
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus
Mol.Wt.: 108 kDa; 108kD(Calculated).
Uniprot: P22102
RRID: AB_2845575

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
GART Antibody detects endogenous levels of total GART.
RRID:
AB_2845575
Cite Format: Affinity Biosciences Cat# DF12613, RRID:AB_2845575.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; GAR transformylase; GARS; GART; GARTF; Glycinamide ribonucleotide synthetase; MGC47764; PAIS; PGFT; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylglycinamide formyltransferase; Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; Phosphoribosylglycinamide synthetase; PRGS; PUR2_HUMAN; Trifunctional purine biosynthetic protein adenosine 3;

Immunogens

Immunogen:
Uniprot:

P22102(PUR2_HUMAN) >>Visit HPA database.

Gene(ID):
GART(2618)
Sequence:
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISISDHTALAQFCKEKKIEFVVVGPEAPLAAGIVGNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEAQALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAIKFEGAIYRKDVGFRAIAFLQQPRSLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTVQLGENGKICWVKEE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P22102 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S10 Phosphorylation
R13 Methylation
K20 Methylation
K20 Ubiquitination
K28 Acetylation
K28 Ubiquitination
C41 S-Nitrosylation
S42 Phosphorylation
K44 Ubiquitination
K63 Ubiquitination
K65 Ubiquitination
K66 Ubiquitination
C93 S-Nitrosylation
K107 Acetylation
K107 Ubiquitination
K111 Ubiquitination
R116 Methylation
T121 Phosphorylation
K125 Methylation
K125 Ubiquitination
K129 Ubiquitination
K148 Ubiquitination
K156 Ubiquitination
K162 Ubiquitination
K169 Ubiquitination
K219 Acetylation
K219 Ubiquitination
T230 Phosphorylation
K249 Ubiquitination
K251 Ubiquitination
K281 Ubiquitination
K285 Ubiquitination
C298 S-Nitrosylation
Y348 Phosphorylation
T349 Phosphorylation
K350 Acetylation
K350 Ubiquitination
K375 Ubiquitination
K378 Ubiquitination
S398 Phosphorylation
K404 Ubiquitination
K405 Ubiquitination
K411 Ubiquitination
Y417 Phosphorylation
K419 Ubiquitination
R433 Methylation
K438 Ubiquitination
S440 Phosphorylation
K452 Ubiquitination
K453 Ubiquitination
K459 Ubiquitination
S464 Phosphorylation
K467 Ubiquitination
K480 Methylation
K480 Ubiquitination
K485 Ubiquitination
T498 Phosphorylation
K499 Ubiquitination
K501 Ubiquitination
K557 Ubiquitination
K561 Ubiquitination
K598 Ubiquitination
S625 Phosphorylation
K633 Ubiquitination
S672 Phosphorylation
K676 Ubiquitination
T682 Phosphorylation
K697 Ubiquitination
S714 Phosphorylation
S723 Phosphorylation
K743 Ubiquitination
K757 Ubiquitination
K779 Ubiquitination
S784 Phosphorylation
S796 Phosphorylation
T798 Phosphorylation
S802 Phosphorylation
K844 Acetylation
K852 Acetylation
K852 Ubiquitination
R855 Methylation
T860 Phosphorylation
K866 Ubiquitination
K910 Ubiquitination
K977 Ubiquitination
K982 Acetylation

Research Backgrounds

Family&Domains:

In the N-terminal section; belongs to the GARS family.

In the central section; belongs to the AIR synthase family.

In the C-terminal section; belongs to the GART family.

Research Fields

· Human Diseases > Drug resistance: Antineoplastic > Antifolate resistance.

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > One carbon pool by folate.

· Metabolism > Global and overview maps > Metabolic pathways.

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